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Packet M: Bonus 14

To begin one process, one of these proteins is phosphorylated by GCN2, HRI, and protein kinase R. For 10 points each:
[10h] What proteins include the only protein that has the nonstandard amino acid hypusine, and another labelled “4A” that is the original DEAD-box helicase? PERK phosphorylates the alpha subunit of one of these proteins to halt the cell cycle and activate the unfolded protein response.
ANSWER: eukaryotic initiation factors [or eIFs; accept eIF2 or eIF4A or eIF5A or eukaryotic initiation factor 2 or eukaryotic initiation factor 5A or eukaryotic initiation factor 4A]
[10e] eIF2 is part of a complex that binds to the 40S subunit to begin translation in these structures, which synthesize proteins from mRNA transcripts.
ANSWER: ribosomes
[10m] The initiator tRNA and eIF2 form a tertiary complex with this molecule at the start of translation. Hydrolysis of this molecule at the head of tubulin heterodimers leads to a “catastrophe” that causes dynamic instability.
ANSWER: GTP [or guanosine triphosphate]
<Cambridge A, Biology> | Packet-M_Cambridge-A_Illinois-A_Johns-Hopkins_Michigan-B_Northwestern-A_Notre-Dame-B_Toronto-B

HeardPPBE %M %H %
3811.5882%26%8%

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Georgia Tech CBruin A010010E

Summary

TournamentEditionMatchHeardPPBE %M %H %
California2025-02-01✓320.00100%67%33%
Lower Mid-Atlantic2025-02-01✓68.3383%0%0%
Midwest2025-02-01✓615.0083%50%17%
Northeast2025-02-01✓512.0080%40%0%
Pacific Northwest2025-02-01✓25.0050%0%0%
South Central2025-02-01✓210.00100%0%0%
Southeast2025-02-01✓110.00100%0%0%
UK2025-02-01✓514.0080%40%20%
Upper Mid-Atlantic2025-02-01✓88.7575%13%0%