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Assays for measuring the activity of this compound based on BRET and FRET methods include CAMYEL and FlCRhR (“flicker”). By forcing one enzyme to bind to calmodulin, a virulence factor produced by members of the genus Bordetella increases levels of this compound. The enzyme that produces this compound can be stimulated using Forskolin, and is activated by the A subunit of cholera toxin, (10[1])which increases intracellular levels of this compound by over 100-fold. Low glucose levels cause this molecule to allosterically bind to CRP as part of a positive regulation mechanism. Phosphodiesterases most commonly act on this compound, which (10[1])is necessary for the activity of protein kinase A. For 10 points, name this secondary messenger molecule made from ATP (10[1]-5[1])by (10[1])adenylyl cyclase. ■END■

ANSWER: cyclic AMP [or cAMP; or cyclic adenosine monophosphate; prompt on AMP]
<MS, Biology>
= Average correct buzz position

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Buzzes

PlayerTeamOpponentPositionValue
Yashwanth BajjiMichigan AMichigan State6110
Jayden KuCarnegie Mellon BMichigan D9710
David NiemanCarnegie Mellon AOhio State A11710
Aditya PatnaikOhio State BKenyon117-5
Enina EdosomwanCase Western ACase Western B11810

Summary

TournamentEditionTUHConv. %Neg %Average Buzz
California2025-02-013100%0%84.67
Great Lakes2025-02-01580%20%98.25
Lower Mid-Atlantic2025-02-01683%50%105.60
Midwest2025-02-016100%17%84.33
North2025-02-01333%33%121.00
Overflow2025-02-01580%60%89.50
Pacific Northwest2025-02-012100%50%107.50
South Central2025-02-012100%0%92.50
Southeast2025-02-01475%50%119.67
UK2025-02-01580%20%87.50
Upper Mid-Atlantic2025-02-01875%25%92.17
Upstate NY2025-02-01367%0%111.00