Bonus

Description acceptable. Hoogsteen (“HOHG-stain”) base pairing allows B-form DNA to take on this characteristic by forming an alternative adenine–thymine bond. For 10 points each:
[10m] Name or describe this characteristic sometimes observed in satellite DNA that may cause genetic instability by interfering with transcription. A disproven theory posited by Linus Pauling claimed that DNA has this structural characteristic.
ANSWER: triple helix [accept triple-stranded DNA or RNA; accept H-DNA or Triplex-DNA]
[10e] Karst Hoogsteen reported his namesake base pairing by observing an alternative one of these interactions between adenine and thymine. These intermolecular interactions are named for the lightest element.
ANSWER: hydrogen bonds [or H-bonds]
[10h] Hoogsteen base pairs also allow for the formation of G-quadruplex secondary structures, which are useful in the design of these artificial oligomers that target a specific ligand. These molecules are produced in a technique called SELEX.
ANSWER: aptamers
<MS, Biology>

EditionsHeardPPBEasy %Medium %Hard %
11518.67100%60%27%

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Conversion

TeamOpponentPart 1Part 2Part 3TotalParts
Brandeis AHarvard B010010E
Brandeis BHarvard A010010E
Carnegie Mellon BCarnegie Mellon A010010E
Case Western AMichigan A010010E
Chicago BIllinois C1010020ME
Illinois AChicago D10101030MEH
Indiana BChicago A1010020ME
KenyonMichigan D010010E
MIT ABrown A10101030MEH
Michigan BOhio State A010010E
Michigan CCase Western B1010020ME
Ohio State BMichigan State1010020ME
Virginia AVirginia Tech A1010020ME
WashU AIndiana A10101030MEH
WashU BMissouri S&T10101030MEH

Summary

TournamentEditionHeardPPBEasy %Medium %Hard %
Great Lakes2025-02-01613.33100%33%0%
Lower Mid-Atlantic2025-02-01120.00100%100%0%
Midwest2025-02-01526.00100%100%60%
Northeast2025-02-01316.67100%33%33%